STATISTICS SEMINAR :: Analysis and Design of HIV Viral Dynamic Studies

GUEST LECTURER
Professor Sarah Holte

AFFILIATION
Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA

ABSTRACT
I will give a brief introduction to the biology of HIV and related dynamical systems problems. This will include a description of statistical methods used for analyzing data when the outcome of interest is a parameter in a dynamical system. I will then describe associated study design problems and discuss the use of sensitivity analysis and the Fisher Information Matrix to address study design and analysis when the outcome of interest is a parameter in a dynamical system. While the examples in this talk are all drawn from the HIV research literature, the methods are applicable to any problem involving design, parameter estimation (inverse problem) and inference, when outcomes of interest are parameters in systems of ordinary differential equations.

Bio
Professor Sarah Holte from the Fred Hutchinson Cancer Research Center (FHCRC) and the University of Washington (UW), Seattle, WA will visit ISyE on Thursday and Friday (Nov 9 and 10). Professor Holte is the associate director of the Biostatistics Core of the UW/FHCRC Center for AIDS Research (CFAR). She got her PhD in mathematics (topology), and switched to biostatistics around ten years ago. Some believe she has a natural ability to "translate" biological problems into mathematics / statistics problems.

If you or a group of you would like to meet with her on either this Thursday (Nov 9) or this Friday (Nov 10), please email Yajun Mei at ymei@isye.gatech.edu to work out a feasible schedule.

DATE & TIME
Friday, November 10, 2006 -- 12:00 PM

DURATION
1 hour

LOCATION
Executive classroom of Main building of ISyE, GT

CONTACT PERSON
Yajun Mei